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Description
IgG1 Fc (NNAS) Protein, HumanProduct Specification Species Human Synonyms IgG1 Fc, Ig gamma 1 chain C region, IGHG1 Accession P01857 Amino Acid Sequence Thr21 Ile192 (S82N, T83A, Y84S) PKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNNASRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK Expression System HEK293 Molecular Weight 30 33kDa Purity >95% by
Product Specification
| Species | Human |
| Synonyms | IgG1 Fc, Ig gamma-1 chain C region, IGHG1 |
| Accession | P01857 |
| Amino Acid Sequence | Thr21-Ile192 (S82N, T83A, Y84S) PKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNNASRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 30-33kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
Immunoglobulin G (IgG) is one of the most abundant proteins in human serum, accounting for about 10–20% of plasma protein. Immunoglobulin G (IgG) is a monomer immunoglobulin, mainly involved in secondary antibody reaction, plasma B cell synthesis and secretion, constitute 75% of human serum immunoglobulin. There are four subtypes of human IgG antibodies: IgG1, IgG2, IgG3, IgG4; mice IgG can be divided into five subtypes; IgG1, IgG2A, IgG2B, IgG2C and IgG3; rats have four subtypes: IgG1, IgG2A, IgG2B and IgG2C. The nomenclature of IgG subtypes of different species is independent, so there is no correlation among different genera. The content of IgG1 in serum accounts for about 60%, and the half-life in serum is about 21 days. After pepsin cleavage, IgG1 is divided into two antigenic binding sites F (ab) s and a highly conserved Fc fragment, and Fc has a highly conserved N-glycosylation site. IgG1 is the most potential subtype in tumor immunotherapy. The active form of IgG1 is bivalent monomer, and human IgG1 can also bind to mouse Fc γ receptor, so the obvious effect can be observed in mouse model.
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4.7 ★★★★★
Based on 14 reviews
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Product Reviews
★★★★★ 5
Solid case.
Color: Sky-Blue
Love this case. Fits great and the color is great! The keyboard is nice and it even has a little spot for a stylist.
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Reviewed in the United States on June 3, 2026
★★★★★ 4
Cheap and good
Color: Black, Color: Black
I chose the color black and it gives a really nice look, especially with the multicolor led lights around the keys. It is very easy to clean and you can shut off the keyboard to prevent any mess with the iPad. The magnet is very nice and keeps the keyboard in place. The keyboard doesn’t easily slip or anything so it holds the iPad very well. Only bad thing is that over time the iPad begins to scrape off the pain and it leaves your keyboard with some white spots all over :/ but if looks isn’t something that you care about, this is the keyboard for you. Don’t use it for gaming because there is a delay in functionality when you press a key and then try to use the pad. Also, you have to press the keys a bit harder than the usual keyboard. But for the price? This is a great item! Definitely worth my money
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Reviewed in the United States on January 18, 2026
★★★★★ 5
Great quality at a remarkable price
Color: Navy Blue
I got an iPad and was looking for a cover to protect it. I came across this case that has a Bluetooth keyboard. It seems to be working great. It was less than $30 and had 4.5 stars with over 4k reviews.
The keyboard is magnetic and detachable, so I’ve got lots of configuration options. The keyboard pairs easily and allows you to use the iPad like a laptop. The point of an iPad a lot in one shot is kind of the touchscreen, but when I’m typing a lot of text as once (like now), it’s really nice to have a physical keyboard and touchpad. The keys are comfortably spaced and I’m comfortable typing on it. There is no additional setup for the keyboard besides pairing it to the iPad. At that point, all the cursor and keyboard features are immediately available.
The case is well built and has nice features like a slot to hold a stylus and multiple grooves to set your viewing angle. It’s configured to be used in landscape mode, but if for some reason you wanted to use it in portrait mode, you can pop the keyboard off to lay it flat. Especially for the price, this is an exceptionally nice iPad cover.
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Reviewed in the United States on May 8, 2026
★★★★★ 5
💪🏼💪🏼🇺🇸🇺🇸🇺🇸
Color: Navy Blue
⭐️⭐️⭐️⭐️⭐️
Very high-quality product, ideal for all types of heavy-duty work. It feels strong, comfortable, and durable. It performs its function perfectly and exceeds expectations. I highly recommend it for its excellent performance and great value for the pr
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Reviewed in the United States on May 10, 2026
★★★★★ 5
Pink IPad Case
Color: Pink
Great case. My iPad feels very safe in this case compared to my other ones. Easy to clean and the color matches the picture.
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Reviewed in the United States on June 8, 2026