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Description
Claudin18.2 Recombinant Rabbit mAb (SDT-102-24)Product Specification Host Rabbit Antigen Claudin18. 2 Synonyms N A Immunogen Synthetic Peptide Location Membrane Accession P56856 2 Clone Number SDT 102 24 Antibody Type Rabbit mAb Application IHC P, IF Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 20 C as supplied
Product Specification
| Host | Rabbit |
| Antigen | Claudin18.2 |
| Synonyms | N/A |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | P56856-2 |
| Clone Number | SDT-102-24 |
| Antibody Type | Rabbit mAb |
| Application | IHC-P, IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:1000 | |
| IF | 1:500 |
Background
Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. Isoform 2 (Claudin 18.2) is abundant in gastric tumors. Claudin 18.2 is involved in tumor development and progression and located in the outer cell membrane. It has exposed extracellular loops and is available for monoclonal antibody binding.
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