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Description
CA125 Recombinant Rabbit mAb,PBS Only (SDT-555-41)Product Specification Host Rabbit Antigen CA125 Synonyms Mucin 16, MUC 16, Ovarian cancer related tumor marker CA125, Ovarian carcinoma antigen CA125, MUC16, Cancer antigen 125 Immunogen Synthetic Peptide Location Secreted, Cell membrane, Extracellular space Accession Q8WXI7 Clone Number SDT 555 41 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance
Product Specification
| Host | Rabbit |
| Antigen | CA125 |
| Synonyms | Mucin-16, MUC-16, Ovarian cancer-related tumor marker CA125, Ovarian carcinoma antigen CA125, MUC16, Cancer antigen 125 |
| Immunogen | Synthetic Peptide |
| Location | Secreted, Cell membrane, Extracellular space |
| Accession | Q8WXI7 |
| Clone Number | SDT-555-41 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC | 1:500 |
Background
Mucin-16 (MUC-16), also known as ovarian cancer associated tumor marker CA125, is a protein encoded by the MUC16 gene. MUC-16 is a member of the glycoprotein family of mucins. MUC-16 has been applied as a tumor marker or biomarker, which may be elevated in the blood of certain types of cancer patients, especially those with cancer or other benign diseases. Detecting CA-125 blood levels is considered useful for treating ovarian cancer. Although this test can provide useful information for women who are known to have cancer, due to the uncertain correlation between CA-125 levels and cancer, the CA-125 test has not been found to be useful as a screening method. In addition to ovarian cancer, CA-125 also increases in patients with endometrial cancer, fallopian tube cancer, lung cancer, breast cancer, and gastrointestinal cancer. Pregnant women may also experience this condition in their bodies. Due to the fact that serum levels can be increased under various circumstances, CA-125 is not used for cancer detection, but it is typically used to monitor ovarian cancer patients' response to chemotherapy, recurrence, and disease progression.
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