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Description
RBPMS Recombinant Rabbit mAb (S-2387-163)Product Specification Host Rabbit Antigen RBPMS Synonyms RNA binding protein with multiple splicing; RBP MS; Heart and RRM expressed sequence (Hermes); HERMES Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession Q93062 Clone Number S 2387 163 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms, Rt Positive Sample HepG2, A549, A431, HeLa, mouse heart, rat heart Purification Protein A Concentration 2 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Antigen | RBPMS |
| Synonyms | RNA-binding protein with multiple splicing; RBP-MS; Heart and RRM expressed sequence (Hermes); HERMES |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | Q93062 |
| Clone Number | S-2387-163 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | HepG2, A549, A431, HeLa, mouse heart, rat heart |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
Background
RBPMS (RNA-binding protein with multiple splicing) is a vertebrate-conserved RNA-binding protein that harbors a single, ~80-aa RNA-recognition motif (RRM) flanked by N- and C-terminal extensions rich in prolines, is expressed as numerous mRNA and protein isoforms from a >230-kb locus, and functions as a master post-transcriptional regulator by directing alternative splicing, stability and translation of target mRNAs critical for cardiac, smooth-muscle, retinal ganglion cell and oocyte development, as well as for DNA-damage responses through interactions with RIF1 and modulation of TGF-β/BMP signaling pathways.
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