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Description
IL-13 Protein, MouseProduct Specification Species Mouse Synonyms Interleukin 13, ALRH Protein, Human; IL 13 Protein, Human; P600 Protein, Human Accession P20109 Amino Acid Sequence Ser26 Phe131 Expression System E. coli Molecular Weight 12kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM PB, 300mM NaCl, pH6. 0 Reconstitution Reconstitute at 0. 1 1 mg ml according to the
Product Specification
| Species | Mouse |
| Synonyms | Interleukin-13, ALRH Protein, Human; IL-13 Protein, Human; P600 Protein, Human |
| Accession | P20109 |
| Amino Acid Sequence | Ser26-Phe131 |
| Expression System | E.coli |
| Molecular Weight | 12kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM PB, 300mM NaCl, pH6.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage |
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1.Cells. 2021 Nov 3;10(11):3000. |
Background
IL-13 is the signature cytokine of the type II inflammatory response. It is key player in the inflammatory response triggered either by an invading parasite or allergen. The cellular sources of IL-4 and IL-13 have been studied extensively and along with CD4 T cells, basophils, eosinophils, mast cells, and NK T cells, appropriately stimulated ILC2 cells have the ability to produce IL-4 and IL-13. IL-13 belong to the T helper 2 (Th2) cytokine family, along with IL-3, IL-5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important immunomodulatory activities and exert influence on a wide variety of immune cells, such as B cells, eosinophils, basophils, monocytes, fibroblasts, endothelial cells, airway epithelial cells, smooth muscle cells, and keratinocytes.
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