Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 9 - Jul 14
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
HRSVA (strain A2) pre-fusion glycoProtein F0 His Tag ProteinProduct Specification Synonyms Prefusion glycoprotein F0 pre F protein (RSV) Accession ACO83301. 1 Amino Acid Sequence Gln26 Leu513 with His Tag at the C Terminus. Some mutations are introduced to stabilize the trimeric prefusion state of RSV Fusion glycoprotein. Expression System HEK293 Molecular Weight 55 72kDa (Reducing) Purity 90% by SDS PAGE Conjugation Unconjugated Tag His Tag Physical Appearance Liquid Storage Buffer PBS, PH7. 4 Reference
Product Specification
| Synonyms | Prefusion glycoprotein F0/pre-F protein (RSV) |
| Accession | ACO83301.1 |
| Amino Acid Sequence | Gln26-Leu513 with His Tag at the C-Terminus. Some mutations are introduced to stabilize the trimeric prefusion state of RSV Fusion glycoprotein. |
| Expression System | HEK293 |
| Molecular Weight | 55-72kDa (Reducing) |
| Purity | ＞90% by SDS-PAGE |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, PH7.4 |
| Reference | Capella C, Chaiwatpongsakorn S, Gorrell E, Risch ZA, Ye F, Mertz SE, Johnson SM, Moore-Clingenpeel M, Ramilo O, Mejias A, Peeples ME. Prefusion F, Postfusion F, G Antibodies, and Disease Severity in Infants and Young Children With Acute Respiratory Syncytial Virus Infection. J Infect Dis. 2017 Dec 12;216(11):1398-1406. |
Background
Human respiratory syncytial virus (HRSV) is the predominant etiological agent of acute lower respiratory tract infections in infants and demonstrates capacity for recurrent infections throughout life. The RSV fusion glycoprotein (RSV F) serves as the primary target for neutralizing antibodies in human sera. As a class I viral fusion protein, RSV F is synthesized as an inactive single-chain polypeptide that undergoes trimeric assembly.Membrane fusion is mediated through an irreversible conformational rearrangement from a metastable prefusion state to a stable postfusion conformation. Both structural states present distinct epitopes recognized by neutralizing antibodies. Notably, the postfusion RSV F conformation is currently under development as a promising vaccine candidate due to its structural stability and immunogenic properties
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy