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Description
CD20 Recombinant Rabbit mAb,PBS Only (SDT-038-205)Product Specification Host Rabbit Antigen CD20 Synonyms B lymphocyte antigen CD20, B lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu 16, Membrane spanning 4 domains subfamily A member 1, MS4A1 Immunogen Synthetic Peptide Location Cell membrane Accession P11836 Clone Number SDT 038 205 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IP Reactivity Hu Purification Protein A Concentration 1 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Antigen | CD20 |
| Synonyms | B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, MS4A1 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P11836 |
| Clone Number | SDT-038-205 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 | |
| IHC-P | 1:1000 |
Background
B-lymphocyte antigen CD20 or CD20 is expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. CD20 is expressed on all stages of B cell development except the first and last; it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells. It is found on B-cell lymphomas, hairy cell leukemia, B-cell chronic lymphocytic leukemia, and melanoma cancer stem cells. Immunohistochemistry can be used to determine the presence of CD20 on cells in histological tissue sections. Because CD20 remains present on the cells of most B-cell neoplasms, and is absent on otherwise similar appearing T-cell neoplasms, it can be very useful in diagnosing conditions such as B-cell lymphomas and leukaemias.
Shipping Notes
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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