SKU: 5182957888

SS18-SSX Recombinant Rabbit mAb, PBS Only (SDT-4202)

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Description

SS18-SSX Recombinant Rabbit mAb, PBS Only (SDT-4202)Product Specification Host Rabbit Antigen SS18 SSX Synonyms SYT SSX1; SS18 SSX1 fusion; SSX1 SSXT fusion Location Nucleus Accession A4PIV8 Clone Number SDT 4202 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt reconstitution, 4C as supplied Dilution

Product Specification


Host Rabbit
Antigen SS18-SSX
Synonyms SYT-SSX1; SS18/SSX1 fusion; SSX1/SSXT fusion
Location Nucleus
Accession A4PIV8
Clone Number SDT-4202
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Hu
Purification Protein A
Concentration 1 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS
Stability & Storage

12 months from date of receipt / reconstitution, 4°C as supplied

Dilution


application dilution species
WB 1:1000 Hu
IHC-P 1:500 Hu

Background

The SS18-SSX fusion protein is the defining oncogenic driver of synovial sarcoma, arising from the chromosomal translocation t(X;18)(p11;q11) that fuses the SS18 gene on chromosome 18 with SSX1, SSX2, or rarely SSX4 on the X chromosome, producing a chimeric protein in which the C-terminal 8 amino acids of SS18 are replaced by 78 residues from SSX; this fusion retains the N-terminal SNH domain of SS18 that mediates incorporation into SWI/SNF (BAF) chromatin-remodeling complexes, but the SSX moiety recruits polycomb repressive complexes (especially PRC1.1 via KDM2B) and binds H2AK119ub-rich regions, thereby hijacking BAF targeting to aberrantly activate developmentally repressed genes, evict the tumor-suppressive BAF47 (SMARCB1/INI1) subunit, and globally reprogram the epigenetic landscape to enforce malignant transformation.

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Exchange/Return Notes
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SKU: 5182957888

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4.0 ★★★★★
Based on 24 reviews
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B
Verified Purchase
BGRLZRK
Belleville, US
★★★★★ 4
Looks and feels AMAZING! Better than the ad.
Color: purple, Color: purple
Recap... After a few months... The wheel is still Flufftabulous... There's a lot of lint accumulation on the dash and areas around the wheel but nothing like the shedding of my previous wheel. If this one ever wears completely out which i doubt... I'd definitely re-order. It arrived the next day as promised. Vacuum sealed packaging so I opened it and brushed them out. There was minimal shedding while brushing. I was relieved since this is my 2nd fuzzy wheel ... the first was more of a shag carpet type of fur which was fluffy and fabulous but left tons of lint and dust bunnies. After 2 days there's been minimal to no shedding. It was easy to put on my standard sized steering wheel and fits snug and secure NO SLIPPING! I only gave it 4 starts because the gear shift cover could be fluffier. We'll see how it all holds up in GA heat. I'm happy with it so far, if anything changes .. I'll be back. I almost forgot... I included a pic to show the view of my dashboard isn't compromised at the position I have my s.w. in which is the highest level. If you like your wheel down in your lap, your dash won't be visible. Hope this helps... Enjoy Flufftabulous Wheel!
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Reviewed in the United States on October 3, 2018
J
Verified Purchase
Jason D. Carroll
Whiting, US
★★★★★ 5
POLYESTER?!?!
Color: Ivory, Size: 2' x 3' (Pelt), Color: Ivory, Size: 2' x 3' (Pelt)
POLYESTER?!?! So i just bought several of these. Nice and big and fluffy, looked very clean, very nice. Cats instantly were scared/curious. The back of the skin, the wool, all looked nice, and then I noticed it had a tag on it... The tag says... 100% POLYESTER! What?!?!? This is supposed to be New Zealand Sheep Skin pelt! Shouldnt be any Polyester at all. So, just before I was about to return it, i did a small burn test. I cut off a small bunch of hair and burned it. The fire tried to light but it quickly extinguished itself. And the smell... yes... the smell told me it is REAL WOOL and the fact the fire went out right away also confirms this is not oil based. THIS IS REAL, This is NOT Polyester. I guess also a lot of ppl are returning because of the tag, so these are at a HUGE DISCOUNT!!! BUY THEM UP!!! They also came in vacuum packed bags, looked nice and kept very nice. These are excellent! See my photos, the tag, the burned bunch of hair... fire went out, i tried it three times, fire kept instantly going out... smells organic like animal hair when burned, not like oil/polyester. ENJOY!!! I PAID FOR THESE, I was not given anything here!
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Reviewed in the United States on September 1, 2025
D
Verified Purchase
Dee
Omaha, US
★★★★★ 5
Love this product!
Color: Linen, Size: 2' x 3' (Pelt)
This sheepskin elevated a boring leather couch to a luxurious sitting space! I purchased 2, one for each loveseat, as sometimes the leather is a little cold. The sheepskin with a small lumbar pillow and voila! A cozy place everyone gravitates to! The sheepskin is soft and cozy and everyone comments they want one! ha probably will get this as a couple of gifts (for those guests that said they wanted one too)
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Reviewed in the United States on May 15, 2026
L
Verified Purchase
Laney
Draper, US
★★★★★ 5
Perfect sheepskin rug
Color: Ivory, Size: 2'3" x 3'5" (Large Pelt)
This sheepskin rug is fabulous! I have it over my office chair and I LOVE it. It does not shed, it stays in place and fits over the seat and up the entire back of the chair with a bit remaining to hang over the edge. My cat sleeps on it every chance he gets. Great value for the price! Just looking at it brings me joy, such a beautiful sheepskin.
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Reviewed in the United States on May 6, 2026
F
Verified Purchase
FRECKLEFRACK
Chelsea, US
★★★★★ 5
Dog ignores, but I like
Color: Ivory, Size: 2' x 3' (Pelt), Color: Ivory, Size: 2' x 3' (Pelt)
I bought this for my dog, who is old and has creaky joints. My dog prefers to continue resting in uncomfortable places that put my plants in peril. He does not ever recline on this dead sheep and looks at me as though I am the sheep slaughterer. Spouse asked if it came in bigger sizes. Since this is the skin of a dead sheep, it depends on live sheep girth. Anything bigger would likely have to be sewn together from multiple dead sheep. I find the girth of this sheep pelt perfectly acceptable. It is nice and thick and soft and fairly easy to vacuum. I frequently recline on it when stretched out on the floor, and am grateful it does not leave a mess or make noise like my dog, who should be grateful that his pelt is still attached to his body.
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Reviewed in the United States on January 4, 2024

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