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Description
K9 Advantix II XL Dog Flea, Tick & Mosquito Treatment & PreventionK9 Advantix II Extra Large Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing
K9 Advantix II Extra Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Extra Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use K9 Advantix II Extra Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Extra Large Dog is a trademark of Elanco or its affiliates.
Key Features
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K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
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Kills fleas within 12 hours of application
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Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
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Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
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No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Extra Large
Pet Lifestage
- 7 weeks and older
Pet Weight
Over 55 lbs
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.7 ★★★★★
Based on 15 reviews
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Product Reviews
★★★★★ 5
Well made, minor issue was quickly resolved
Size: Large, Color: Dinos Bruto (Purple)
I purchased the Dino Bruto Dog toy for my labradoodle who is quite fond of squeaky, squawky stuffed toys and oddly enough has shown a preference for purple. I opened the package with my hound standing by waiting for his gift. I detached the tags and attempted to squeak the toy. It seemed difficult to squeak or honk. I tossed the purple Dino Bruto to my dog who excitedly chomped to squeak. The toy squawked a couple times and then just quit. My poor hound was staring up at me with that "what's up with this" look on his face. I tracked down the website for the GoDog toys, not going through the Amazon return process. I called the good people at GoDog and stated simply that my dog's favorite part of the toy failed quite quickly and I was wondering about guarantees. I was told to go to the website and file a replacement request. The replacement request required that I include a photo which I did as directed. I received an reply email within a couple hours which stated that a new toy would be sent out shortly.
I am happy to report that we received a replacement toy, not the purple Dino, but a colorful wood duck. The squawker device works well and is still performing like new more than a month later.
It appears that the squeaker is not those little plastic squeakers but the bigger heavy plastic bag, bladder, with what I visualize as a duck call sort of sound device. I am guessing because I haven't seen the inside of the GoDog toys. I have seen the guts of other stuffed toys which use this type of noise device. While our dog seems to enjoy the sound of the plastic bag, bladder set-up squawkers, they seem to fail quickly and I tend to avoid them because of this. The toys using this type of squawker that I have seen, use what looks like a cheap lightweight plastic bag which is not securely attached to the "voice box".
Since the GoDog replacement toy is holding up so well, I am guessing GoDog uses a heavier grade plastic bladder coupled with reinforced construction. The purple Dino Bruto toy still looks new even after multiple times of our hound grabbing the purple toy, shaking it at us with his invite to give chase or play keep away. Since the squawker failed so quickly with the new toy, I figure it was just a defective item which does not reflect the general quality of toys from GoDog.
One evening our neighbor was visiting while his pitbull was playing in our yard with our dog. Our patio door was open so our dog ran into the house and grabbed his purple Dino Bruto toy. He is a bit of a show-off with new toys. Our dog then went racing back into the yard, shaking his GoDog toy at the pitbull. A quick game of tug-of-war ensued. Since this is a new toy, our neighbor leaped into the game and took the toy away from the dogs. In that short time of tugging between the dogs, the toy held together and did not even pull apart at any of the seams. There were no puncture marks either.
This is a game our dog has initiated before with the neighbor pitbull. Normally, the stuffed toys are ripped apart almost immediately. I was surprised and impressed with the quality of the sewing which appears to employ some sort of reinforced construction or heavier material.
I plan to make more purchases from GoDog toys. The toys are a little more expensive than some stuffed dogs toys but they hold up so well I figure they are worth a few more dollars. They are great toys that hold up well and the company provides quick responses to inquiries. I consider this a winning combination.
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Reviewed in the United States on June 15, 2013
★★★★★ 5
Good quality
Size: Large, Color: Dinos Frills (Gray)
we’ve had many godog toys over the years and although my dog eventually rips through them I do find that they last longer than other cheap toys. Overall very well made!
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Reviewed in the United States on May 11, 2026
★★★★★ 5
Cute and fairly long lasting
Size: Large, Color: Dinos Frills (Red)
Lasted from Nov 13th, 2024-August 20th, 2025 lol very impressive. She played with it nearly daily and loved the big squeak. The squeak box was just ripped out so she probably won’t play with it anymore. Happy to order another!
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Reviewed in the United States on August 21, 2025
★★★★★ 4
He was OBSESSED!!!
Size: Large, Color: Dinos Frills (Gray), Size: Large, Color: Dinos Frills (Gray)
Our year and a half old lab was excited the moment he saw it come out of the box ! He had many toys that he tore into shreds within a day so this was his first “heavy toy “ that wasn’t easy to tear .
I think he loves the design and feel of it , as he carried this thing EVERYWHERE and even to bed . Him and his sister share toys but this was his , he claimed it lol
Now if it wasn’t for us telling him to stop trying to kill the Dino he could have easily tore into this thing within a couple of days . However since he started chewing gently he became obsessed with the squeaker , and used that as an alarm that he was up every morning in bed 😂
The quality of the product is actually pretty good but it’s not bullet proof, and our smart dog was able to sneakily tear a whole in the nose and some how pull out the stuffing .
All in all I would definitely buy another toy from this company because they are made with quality for dogs , and lasted about three weeks longer than his average toys ! It was his favorite toy 💕
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Reviewed in the United States on September 3, 2023
★★★★★ 3
Not indestructible
Size: Large, Color: Dinos Frills (Gray)
When I googled “indestructible stuffy dog toys” this popped up. My 9 month old pup loves stuffies but destroys them quickly and eats stuffing if not caught quickly. Well, this indestructible toy is cute but my dog had it torn apart in under 4 minutes so…🤷🏻♀️
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Reviewed in the United States on January 14, 2026
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