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Description
Mouse Anti-Human CD25 (IL-2Rα) Antibody (S-3707)Product Specification Host Mouse Antigen CD25 Synonyms Interleukin 2 receptor subunit alpha; IL 2 receptor subunit alpha; IL 2 RA; IL 2R subunit alpha; IL2 RA; TAC antigen; p55; IL2RA Location Membrane Accession P01589 Clone Number S 3707 Antibody Type Mouse mAb Isotype IgG2a Application FCM Reactivity Hu Positive Sample Human peripheral blood lymphocytes Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid
Product Specification
| Host | Mouse |
| Antigen | CD25 |
| Synonyms | Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; IL2RA |
| Location | Membrane |
| Accession | P01589 |
| Clone Number | S-3707 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human peripheral blood lymphocytes |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
CD25, also known as IL2RA, is the alpha chain of the interleukin-2 receptor, a heterotrimeric protein complex that also includes beta (IL2RB) and the common gamma chain (IL2RG). It is a membranous glycoprotein primarily expressed on activated T lymphocytes and plays a crucial role in immune homeostasis by interacting with interleukin-2, a pleiotropic cytokine. CD25 is involved in the proliferation of T and B lymphocytes and is essential for the assembly of the high-affinity interleukin-2 receptor. In addition to its role in the immune system, CD25 is also expressed on certain non-immune cells and has been identified as a potential therapeutic target in cancers.
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4.4 ★★★★★
Based on 18 reviews
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Product Reviews
★★★★★ 5
Compelling!
Format: Paperback
I loved this book. It is a personal, honest, beautiful account of walking the Camino, and I didn’t want it to end. The actual reality of walking the Camino is aptly portrayed in this open-hearted story. Angela’s unique turn of phrase, her outrageous humor, her vulnerability, the unrelenting pain, and the lessons learned are beautifully expressed, and are a testament to her endurance and to her Love. Angela has the true heart of a pilgrim, showing us that seeing with eyes of Love is all that matters. Bronwen Diana
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Reviewed in the United States on March 22, 2019
★★★★★ 4
Enjoyable and Uplifting
Format: Kindle
After reading this book, it came to me that this is different and maybe far more uplifting than the prior books I’ve read. It should have been my first book to read but alas, I’ve been reading about the Camino for over a decade. I enjoyed Angel’s perspective on the Camino but also how it affected her life.
If you’ve ever considered the Camino, read this one before you go, and then GO!
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Reviewed in the United States on May 23, 2024
★★★★★ 5
A Vicarious Adventure
Format: Kindle
I’ve read numerous books about the Camino, and most have been excellent, as was this one. The author captured the emotions during interactions with fellow pilgrims insightfully. Ranging from petty squabbles to jealousy to shared misery to elation—you were part of the experience. Easy to read, hard to put down, entertaining.
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Reviewed in the United States on May 4, 2022
★★★★★ 5
A Very Enjoyable Camino Pilgrimage
Format: Kindle
A detailed 40 day journal format of one pilgrims experience upon the Camino Frances. She revisits the various personalities she encountered along the way and discribes the tough terrain and weather challenges which in turn push her to the limits of her physical abilities. In the end, she perseveres and eventually finds a change in the hardness of her heart ...the Camino is known to do this.
Great book and I enjoyed it thoroughly...I purchased both the text and audio versions to read along. I highly recommend it for any potential pilgrims or for anyone seeking to enjoy a 800km hike in Northern Spain. Thanks for bringing me along!
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Reviewed in the United States on March 9, 2021
★★★★★ 5
Well Presented Concepts and Implementations (5th ed.)
Format: Paperback
Foreword: I have been running my own DNS servers on OpenBSD and FreeBSD for about 4 years. All of my previous DNS knowledge was obtained from the man pages and online tutorials.
The book is great because the example network used throughout the book is built upon, showing you how to "grow" your DNS with your expanding network. The design and implementation presented is priceless and covers some of my favorite topics: placement of slaves, hidden primaries, building root servers, split views, daisy-chaining, forwarders, partial-slaves, address maintenance issues, etc. The pros and cons of each setup are weighed and best practices are suggested. If you like a generous helping of diagrams, examples, and tables as a learning aid, you won't be disappointed.
One specific example of weighing the pros and the cons is presented on page 479 as follows:
"Could we have saved a few bucks on hardware by using our external authoritative nameservers as forwarders, too? Sure, but that would have presented a risk." After that statement, they proceed into all the details of "why."
There is adequate coverage on security. The authors preach defense in depth. An implementation example includes hiding your masters and only exposing bastion slaves. Securing communications between the masters and slaves is also covered in the security chapter using DNSSEC and TSIG. I think IPSec is another way to add a security layer, but that is probably another book.
After reading the book, I started to implement my new DNS infrastructure and found myself referring to the index often. It is fairly consummate, however, I found a few things missing, such as the $GENERATE statement. Also, some of the configuration details were lacking slightly. For example, the order in which ACL elements are processed and how negated elements affect the processing outcome. Another question I had was, what would happen if an ACL name is negated, and what if that ACL contained some negated elements. Well I found my answer by actually trying it and verifying with the canonical reference docs on isc.org.
I gave this book five stars because of its effectiveness in presenting the concepts and implementations of DNS using examples, good writing style, tables, and diagrams. If you're looking for the last 4 percent of the diminutive details of DNS, you will find it on isc.org.
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Reviewed in the United States on August 22, 2006