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Description
Neurofilament M Recombinant Rabbit mAb (S-501-31)Product Specification Host Rabbit Antigen Neurofilament M Synonyms Neurofilament medium polypeptide, NF M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein, NEFM, NEF3, NFM Immunogen Synthetic Peptide Location Cytoplasm, Cytoskeleton Accession P07197 Clone Number S 501 31 Antibody Type Recombinant mAb Application WB, IHC P, IP, IF Reactivity Hu, Ms, Rt Predicted Reactivity Bv Purification Protein A Concentration 0. 5 mg
Product Specification
| Host | Rabbit |
| Antigen | Neurofilament M |
| Synonyms | Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein, NEFM, NEF3, NFM |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Cytoskeleton |
| Accession | P07197 |
| Clone Number | S-501-31 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, IP, IF |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Bv |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC | 1:500 | |
| IP | 1:50 | |
| IF | 1:2000 |
Background
Neurofilament medium polypeptide (NF-M) is a protein that in humans is encoded by the NEFM gene. Neurofilaments are type IV intermediate filament heteropolymers composed of light (NEFL), medium (this protein), and heavy (NEFH) chains. Neurofilaments comprise the exoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage.
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