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Description
CTACK/CCL27 Protein, HumanProduct Specification Species Human Synonyms Cutaneous T cell Attracting Chemokine,CCL27,ALP,Skinkine,ESkine Accession Q9Y4X3 Amino Acid Sequence Phe25 Gly112 Expression System E. coli Molecular Weight Approximately 10. 1 kDa, a single non glycosylated polypeptide chain containing 88 amino acids. Purity 96% by SDS PAGE or HPLC. Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH 7. 0. Reconstitution Before
Product Specification
| Species | Human |
| Synonyms | Cutaneous T-cell Attracting Chemokine,CCL27,ALP,Skinkine,ESkine |
| Accession | Q9Y4X3 |
| Amino Acid Sequence | Phe25-Gly112 |
| Expression System | E.coli |
| Molecular Weight | Approximately 10.1 kDa, a single non-glycosylated polypeptide chain containing 88 amino acids. |
| Purity | ＞96% by SDS-PAGE or HPLC. |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, pH 7.0. |
| Reconstitution | Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | For long term storage, the product should be stored ≤ -20℃. |
Background
CCL27, also named IL-11 R-alpha-locus chemokine (ILC) , Skinkine, ESkine and cutaneous T-cell-attracting chemokine (CTACK) , is a small cytokine belonging to the CC chemokine family. CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin and it elicits its chemotactic effects by binding to the chemokine receptor CCR10. CCL27 can attract skin-associated memory T-lymphocytes. Studies showed it may play a role in mediating homing of lymphocytes to cutaneous sites and cell migration during embryogenesis. Mature human CCL27 is an 88 amino acid (a.a.) protein that shares 56% a.a. sequence identity with murine. Recombinant Human CTACK is a 10.2kDa protein containing 88 amino acid residues.
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