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Description
BTN1A1/Butyrophilin His Tag Protein, HumanProduct Specification Species Human Synonyms BTN1A1,Butyrophilin,BTN Accession Q13410 1 Amino Acid Sequence Ala27 Arg242 with His Tag at C Terminus Expression System HEK293 Molecular Weight 30 37kDa(Reducing) Purity > 95% as determined by SDS PAGE & SEC HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Storage Buffer PBS PH7. 4 5% trehalose Stability & Storage 12 months from date of receipt, lyophilized powder stored at 20 to 80. 3
Product Specification
| Species | Human |
| Synonyms | BTN1A1,Butyrophilin,BTN |
| Accession | Q13410-1 |
| Amino Acid Sequence | Ala27-Arg242 with His Tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 30-37kDa(Reducing) |
| Purity | > 95% as determined by SDS-PAGE & SEC-HPLC. |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Storage Buffer | PBS PH7.4 5% trehalose |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | Chu X, Han Z, Li B, Yang T. Plasma proteins and different onset subtype of COPD: Proteome-wide Mendelian randomization study and co-localization analyses. Medicine (Baltimore). 2025 May 9;104(19):e42409. |
Background
BTN1A1, also known as BTN, is a member of the immunoglobulin superfamily and the major milk fat droplet-associated protein. It may function as a cell surface receptor. The human butyrophilin gene, located in the MHC class I region on chromosome 6p, likely originated through exon shuffling between two ancestral gene families. BTN1A1 regulates milk lipid content and droplet size and inhibits proliferation of anti-CD3-activated CD4 and CD8 T-cells, as well as T-cell metabolism and secretion of IL2 and IFNG.
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