SKU: 33241568813

Mouse Anti-Human CXCR6 Antibody (S-3884)

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Description

Mouse Anti-Human CXCR6 Antibody (S-3884)Product Specification Host Mouse Antigen CXCR6 Synonyms C X C chemokine receptor type 6; CXC R6; CXCR 6; CDw186; G protein coupled receptor STRL33; G protein coupled receptor bonzo; CD186; BONZO; STRL33; TYMSTR Location Cell membrane Accession O00574 Clone Number S 3884 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical

Product Specification


Host Mouse
Antigen CXCR6
Synonyms C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD186; BONZO; STRL33; TYMSTR
Location Cell membrane
Accession O00574
Clone Number S-3884
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Hu

Background

CXCR6 (C-X-C motif chemokine receptor 6), also known as STRL33 and T-lymphocyte-expressed seven-transmembrane domain receptor (TYMSTR), is a G protein-coupled receptor (GPCR) that specifically binds to its unique ligand CXCL16, a transmembrane chemokine that can also be cleaved to function as a soluble chemokine. CXCR6 is predominantly expressed on memory/effector T cells, natural killer T (NKT) cells, natural killer (NK) cells, and plasma cells, playing critical roles in immune cell trafficking, adhesion, and activation. The CXCR6-CXCL16 axis is essential for the recruitment and positioning of immune cells in various tissues, particularly in the liver, spleen, and inflamed sites, and has been implicated in numerous pathological conditions including chronic inflammation, autoimmune diseases, infectious diseases, and cancer. In oncology, CXCR6 expression on tumor-infiltrating lymphocytes (TILs) is associated with improved prognosis in certain cancers, while its expression on tumor cells can promote metastasis and disease progression. The receptor signals primarily through Gαi proteins, activating downstream pathways such as PI3K/AKT, MAPK/ERK, and calcium mobilization, thereby regulating cell migration, survival, and proliferation. Given its selective expression on activated immune cells and its involvement in disease pathogenesis, CXCR6 represents an attractive therapeutic target for immunomodulatory strategies and precision medicine approaches.

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SKU: 33241568813

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Amazon Customer
Belleville, US
★★★★★ 5
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I just purchased this and tried it last night for the first time along with the firming version. I didn't take photos because I was skeptical as a product I had purchased from a different line for more money didn't work. This morning I notice that not only does my skin feel more hydrated but the texture appears more smooth. I recently turned 75 & lost my husband a few months ago and having been a care giver for awhile and put taking care of me aside. These products and body wash are great and I like the fragrance. Please give them a try. To have something show this much difference over night is incredible. They are also affordable which is a plus for me. Thank you Olay.
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Reviewed in the United States on April 24, 2026
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Chris
Louisville, US
★★★★★ 5
Wonderful
Scent: Sweet Vanilla & Soft Wood, Size: 18.5 Fl Oz (Pack of 1)
I've only tried it for the first time, so I can't speak to performance, but I love 5his Product! It isn't greasy, it absorbs quickly & my skin feels much softer. The scent is just beautiful. It's light & not closing like some. Recommend highly.
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Reviewed in the United States on May 18, 2026
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Bella Andrea
Carnegie, US
★★★★★ 5
Great option. For less clean up! these are a must
Style: 8.5 Inch, Size: 90 Count (Pack of 1)
Inexpensive, sturdy, perfect instead of heavy dishes. Good versatility and size. Thick and they don’t crumple when a full supper is on them.
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Reviewed in the United States on May 29, 2026
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SHANA DANIELS GARDNER
Whiting, US
★★★★★ 5
Dependable Quality, Great Value - A Household Essential!
Style: 8.5 Inch, Size: 90 Count (Pack of 1)
These Dixie Medium Paper Plates (8.5 Inch, 90 Count) are our absolute go-to, and we always make sure to keep them stocked in our house! The quality is consistently excellent – they truly are 2X stronger, microwave-safe, soak-proof, and cut-resistant, which means no more leaky messes or flimsy plates. You get fantastic reliability without breaking the bank. For everyday meals, parties, or any occasion where you want convenience without sacrificing quality, these are perfect. A great product at a good price point. Highly recommend!
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Reviewed in the United States on May 13, 2026
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Winter
Boise, US
★★★★★ 5
Washable quality paper plates
Style: 10 Inch, Size: 150 Count (Pack of 1)
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Reviewed in the United States on May 25, 2026

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