SKU: 2889091493

SDF1/CXCL12 Recombinant Rabbit mAb, PBS Only (SDT-3675)

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Description

SDF1/CXCL12 Recombinant Rabbit mAb, PBS Only (SDT-3675)Product Specification Host Rabbit Antigen SDF1 CXCL12 Synonyms Stromal cell derived factor 1; SDF 1; hSDF 1; C X C motif chemokine 12; Intercrine reduced in hepatomas (IRH; hIRH); Pre B cell growth stimulating factor (PBSF); SDF1A; SDF1B Location Secreted Accession P48061 Clone Number SDT 3675 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Hu Purification Protein A Concentration 1mg ml Conjugation Unconjugated Physical

Product Specification


Host Rabbit
Antigen SDF1/CXCL12
Synonyms Stromal cell-derived factor 1; SDF-1; hSDF-1; C-X-C motif chemokine 12; Intercrine reduced in hepatomas (IRH; hIRH); Pre-B cell growth-stimulating factor (PBSF); SDF1A; SDF1B
Location Secreted
Accession P48061
Clone Number SDT-3675
Antibody Type Recombinant mAb
Isotype IgG
Application IHC-P
Reactivity Hu
Purification Protein A
Concentration 1mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS
Stability & Storage

12 months from date of receipt / reconstitution, 4 °C as supplied

Dilution


application dilution species
IHC-P 1:250 Hu

Background

Stromal cell-derived factor-1 (SDF-1), also designated CXCL12, is a 67-amino-acid constitutively secreted chemokine that signals exclusively through the Gαi-protein-coupled receptor CXCR4 (and atypical CXCR7) to orchestrate embryonic development, adult stem-cell homing, immune surveillance, vascular remodeling, and neural circuitry; its 3-stranded β-sheet flanked by an α-helix and disulfide-stabilized loops binds CXCR4 with nanomolar affinity, triggering PI3K–Akt, MAPK/ERK, and calcium flux that mediate chemotaxis, survival, and proliferation, whereas dysregulated SDF-1/CXCR4 signaling fuels cancer metastasis, inflammatory disease, and HIV entry, making the pathway a prime target for small-molecule antagonists, peptide analogs, and neutralizing antibodies in oncology and regenerative medicine.

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Exchange/Return Notes
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SKU: 2889091493

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4.7 ★★★★★
Based on 7 reviews
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Product Reviews
J
Verified Purchase
jin
Los Angeles, US
★★★★★ 5
Most comfortable pillow I’ve ever slept on
Size: Queen (1 Count), Color: Crescent White(cooling)
This is the most comfortable pillow I have ever slept on. It doesn't mash down like other pillows. Cradles my neck perfectly plus it’s cool. I broke my neck a couple of years ago and this pillow feels very good and comfortable. Definitely recommend to everyone. Ive used it since May and it’s retained its shape.
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Reviewed in the United States on June 6, 2026
A
Verified Purchase
AreTrue
Pawtucket, US
★★★★★ 4
Smell
Size: Queen (2 Count), Color: Original White (Cooling)
The fact that there are not more comments on the smell of these pillows has me worried about some of yall. Listen, I LOVE the weight, and the firmness, it’s perfect for that. However, these pillows are RANK. They have a very strong mildew-ish smell that lingers. I took the outer cover off and washed it and let the pillow air out for a few days, the smell is still very strong when you press your face against it, which one does because it is in fact designed for that purpose. It smells so bad. It’s nauseating. I can smell it through two pillowcases and blanket that I threw on top of them hoping an extra layer would trap the smell. I’ll bake them in the Texas sun tomorrow and hope that helps, because otherwise these are the perfect pillows for someone who wants to feel like they are hugging a torso but can’t stand the sound/feel of someone else breathing. I don’t know…4 stars, if the smell goes away I’ll come back. Update: many many days later. Either they don’t really smell anymore or I got use to it. They’ve held their firmness and shape well. I like them.
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Reviewed in the United States on March 9, 2026
S
Verified Purchase
Samantha
Lake Worth, US
★★★★★ 5
Actually Cooling Pillow
Size: Queen (1 Count), Color: Original White (Cooling)
This is a really nice pillow, I was worried it would be too soft or too firm but it's just right and it's actually cooling, it feels cool every time I touch it. I've noticed an improvement in sleep since using it. Would recommend!
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Reviewed in the United States on May 27, 2026
T
Verified Purchase
Tyler and Kaela
Belleville, US
★★★★★ 5
Repurchased in King Size – Still Love These Cooling Pillows
Size: King (2 Count), Color: Original White (Cooling), Size: King (2 Count), Color: Original White (Cooling)
After using the queen-size version of these pillows for over a year, we purchased the king-size set when we upgraded to a king mattress. Both my husband and I really like them. The cooling feature works well, and we like that each side feels different—when I run cold, I use the softer bamboo side, while my husband prefers the cooler side since he tends to sleep hot. They fit well in our king-size pillowcases and feel supportive in all sleeping positions, whether I’m on my stomach, side, or back. I also appreciate that you can remove some of the filling to adjust the firmness. The covers are washable, which makes them easy to maintain. Overall, we’re very happy with this repurchase and the long-lasting comfort.
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Reviewed in the United States on April 15, 2026
M
Verified Purchase
Mystery Fan
Waukegan, US
★★★★★ 3
Not great at cooling
Size: Queen (2 Count), Color: Original White (Cooling)
Each pillow cover has 2 sides, one marked for cooling, and the other a different fabric. The cooling side is about the same effectiveness as having a silk or satin pillow cover. It's only cool when you first touch it. The cooling side doesn't seem to absorb or wick moisture, so if you are sweaty - it keeps the moisture in place. You'll definitely want a regular pillow case over the pillow cover. In fact, if you suffer from night sweats, the non-cooling side is actually more comfortable. The pillow fill is ample, and simple to squish around for more support for your neck, etc. Think bean bag. But it will retain your impression after use. I find I need to do as I did when I had down pillows - give it a few good shakes in the morning when I make the bed to get it evened out for the coming night. In all, it is a well-made and comfortable pillow to sleep on, but it does not excel in cooling.
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Reviewed in the United States on May 29, 2026

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