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Description
FITC Mouse Anti-Human CD200 Antibody (S-R582)Product Specification Host Mouse Antigen CD200 Synonyms OX 2 membrane glycoprotein; MOX1; MOX2 Location Cell membrane Accession P41217 Clone Number S R582 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation FITC Physical Appearance Liquid Storage Buffer PBS, 25% Glycerol, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Mouse |
| Antigen | CD200 |
| Synonyms | OX-2 membrane glycoprotein; MOX1; MOX2 |
| Location | Cell membrane |
| Accession | P41217 |
| Clone Number | S-R582 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human PBMC |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | FITC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD200, also known as OX-2, is a type I membrane glycoprotein belonging to the immunoglobulin superfamily. It is widely expressed on various cell types, including B cells, T cells, dendritic cells, neurons, and endothelial cells. CD200 primarily functions through its interaction with CD200R, a receptor expressed on myeloid cells, T cells, and other immune cells. This interaction suppresses T-cell-mediated immune responses, reduces the production of inflammatory cytokines, and promotes immune tolerance. In the context of cancer, CD200 expression on tumor cells can lead to immune evasion by inhibiting antitumor T-cell responses. Additionally, CD200 plays a crucial role in maintaining immune homeostasis and is involved in various autoimmune and inflammatory diseases.
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