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Description
CysC Recombinant Rabbit mAb (S-1658-86)Product Specification Host Rabbit Antigen CysC Synonyms Cystatin C; Cystatin 3; Gamma trace; Neuroendocrine basic polypeptide; Post gamma globulin; CST3 Immunogen Recombinant Protein Location Secreted Accession P01034 Clone Number S 1658 86 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%
Product Specification
| Host | Rabbit |
| Antigen | CysC |
| Synonyms | Cystatin-C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin; CST3 |
| Immunogen | Recombinant Protein |
| Location | Secreted |
| Accession | P01034 |
| Clone Number | S-1658-86 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
Background
Cystatin C (CysC) is a low molecular weight, non-glycosylated basic protein composed of 120 amino acids, with a molecular weight of approximately 13 kDa. It is a member of the cysteine protease inhibitor superfamily and is produced at a constant rate by all nucleated cells in the body. As an endogenous marker, CysC is freely filtered by the glomeruli, reabsorbed and metabolized in the proximal tubules, and does not return to the bloodstream. Its serum concentration is independent of factors such as age, gender, diet, and muscle mass, making it an ideal indicator for assessing glomerular filtration rate (GFR) and early kidney function impairment. Elevated levels of CysC may indicate decreased kidney function, while its stability and sensitivity make it superior to traditional markers like serum creatinine.
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