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Description
NS1 His Tag protein, Dengue virus 2Product Specification Synonyms DEN 2,Dengue NS1 protein,DENV2 NS1,Dengue virus (DENV) (type 2,strain New Guinea C) NS1 Protein Accession O92835 Amino Acid Sequence Asp776 Ala1127 with a polyhistidine tag at the N terminus Expression System HEK293 Molecular Weight 45 50 kDa(Reducing) Purity 95% by SDS PAGE & SEC HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized powder Storage Buffer PBS PH7. 4 5% trehalose
Product Specification
| Synonyms | DEN-2,Dengue NS1 protein,DENV2-NS1,Dengue virus (DENV) (type 2,strain New Guinea C) NS1 Protein |
| Accession | O92835 |
| Amino Acid Sequence | Asp776-Ala1127 with a polyhistidine tag at the N-terminus |
| Expression System | HEK293 |
| Molecular Weight | 45-50 kDa(Reducing) |
| Purity | ＞95% by SDS-PAGE & SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS PH7.4 5% trehalose |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | Niranjan R, Sumitha MK, Sankari T, Muthukumaravel S, Jambulingam P. Nonstructural protein-1 (NS1) of dengue virus type-2 differentially stimulate expressions of matrix metalloproteinases in monocytes: protective effect of paracetamol. Int Immunopharmacol.2019 Aug;73:270-279. |
Background
Dengue virus (DENV) nonstructural protein 1 (NS1) is a 352-amino acid protein that exists in various oligomeric forms and is conserved within the flavivirus family. While extensively studied for its diagnostic potential, the role of NS1 in viral processes like replication and the development of clinical pathologies, including vascular leakage, remains incompletely understood. Many of these functions likely involve interactions with viral and host proteins that are yet to be fully elucidated.
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