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Description
Alexa Fluor® 647 Mouse Anti-Human CD36 Antibody (S-R617)Product Specification Host Mouse Antigen CD36 Synonyms Platelet glycoprotein 4; Fatty acid translocase (FAT); Glycoprotein IIIb (GPIIIB); Leukocyte differentiation antigen CD36; PAS IV; PAS 4; Platelet collagen receptor; Platelet glycoprotein IV (GPIV); Thrombospondin receptor; GP3B; GP4 Location Cell membrane Accession P16671 Clone Number S R617 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human peripheral
Product Specification
| Host | Mouse |
| Antigen | CD36 |
| Synonyms | Platelet glycoprotein 4; Fatty acid translocase (FAT); Glycoprotein IIIb (GPIIIB); Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV (GPIV); Thrombospondin receptor; GP3B; GP4 |
| Location | Cell membrane |
| Accession | P16671 |
| Clone Number | S-R617 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human peripheral blood |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD36 is a transmembrane glycoprotein that serves as a key fatty acid transporter and sensor, playing a crucial role in lipid metabolism. It is involved in the recognition and phagocytosis of lipids by macrophages and has been implicated in inflammatory responses and cardiovascular diseases. CD36 is also expressed in various immune cells and has been shown to regulate autophagy. Additionally, it is highly expressed in several types of cancer, where it promotes tumor progression by facilitating fatty acid uptake, epithelial-mesenchymal transition (EMT), and resistance to anticancer drugs. CD36 has emerged as a potential therapeutic target for metabolic diseases, cardiovascular conditions, and cancer.
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