Pay in installments of $63.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 15 - Aug 20
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Prolactin R/PRLR His Tag Protein, MouseProduct Specification Species Mouse Synonyms Prolactin R, PRLR, PRL R Accession Q08501 Amino Acid Sequence Gln20 Asp229, with C terminal 8*His QSPPGKPEIHKCRSPDKETFTCWWNPGSDGGLPTNYSLTYSKEGEKNTYECPDYKTSGPNSCFFSKQYTSIWKIYIITVNATNEMGSSTSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWVKWLPPTITDVKTGWFTMEYEIRLKSEEADEWEIHFTGHQTQFKVFDLYPGQKYLVQTRCKPDHGYWSRWGQEKSIEIPNDFTLKDGGGSHHHHHHHH Expression System HEK293 Molecular Weight 33 35kDa Purity >95% by SDS PAGE Endotoxin <0.
Product Specification
| Species | Mouse |
| Synonyms | Prolactin R, PRLR, PRL-R |
| Accession | Q08501 |
| Amino Acid Sequence | Gln20-Asp229, with C-terminal 8*His QSPPGKPEIHKCRSPDKETFTCWWNPGSDGGLPTNYSLTYSKEGEKNTYECPDYKTSGPNSCFFSKQYTSIWKIYIITVNATNEMGSSTSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWVKWLPPTITDVKTGWFTMEYEIRLKSEEADEWEIHFTGHQTQFKVFDLYPGQKYLVQTRCKPDHGYWSRWGQEKSIEIPNDFTLKDGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 33-35kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Bole-Feysot C. et al. (1998) Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev. 19(3): 225-268. |
Background
Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. Knockout prolactin receptor gene (PRL-R) mice are animal models for prolactinomas and PRL acts via autocrine/paracrine inhibiting lactotroph proliferation. Recently, variants of the PRL-R were identified in prolactinoma patients and their frequency was higher compared to individuals from the genomic database. As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. The PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.4 ★★★★★
Based on 9 reviews
Sort
Product Reviews
★★★★★ 5
Durable, bouncy, not annoying like squeaky ball & our dogs LOVE them.
Size: Small 2"
Love these and my dogs love them to! Not nearly as noisy as a squeaky ball (thank goodness) and they bounce which are dogs love. They will fetch them, and they will play by tossing it up and pouncing on it when it bounces. They literally entertain themselves with it when we aren't playing fetch. Much more durable than the round rubber / latex squeaky ball / toys.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 17, 2026
★★★★★ 4
Quality item.
Size: Small 2"
These seem to be quality dog toys. I bought them for a friend's chihuahua. My cats were unimpressed, lol. The chihuahua had never seen a ball. He seemed curious, but would not approach this new item. Time will tell.
The bells have a very loud shrill sound, completely unlike any I've ever heard before.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 22, 2026
★★★★★ 5
What I was looking for!
Size: Large 3"
I bought these to continue playing fetch with my blind dog, she loves it! The only downside is the bell has slipped out once in a great while, but is easily reinserted.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 27, 2026
★★★★★ 5
great for our blind dog
Size: Large 3"
our pup is a blind but active senior and these balls have a bell inside so she can continue playing ball! this is the second time i have ordered these.. love um!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 31, 2026
★★★★★ 5
Great toys for dogs or cats
Size: Small 2"
Sturdy, durable toys. My dog loves the jingle. Great size. Fits in her mouth but not so small we have to worry about her swallowing them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 28, 2026
recommand products
Metra 99-3302
19.99
Sara Linen Top in White
89.00
ECS 13 Pin Car Towbar Electrics Wiring Kit For MG MG4 X-Power Hatch 2023-Onwards
160.59
Westfalia Vertical Detachable Towbar For Renault Kangoo Van 2013 To 2015 and Universal 7 Pin Wiring
233.35
Natalie High Rise Bootcut, Petite in Interactive Wash
124.00