Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 10 - Jul 15
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 647 Rat Anti-Mouse CD14 Antibody (S-R609)Product Specification Host Rat Antigen CD14 Synonyms Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein; Cd14 Location Cell membrane Accession P10810 Clone Number S R609 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample RAW 264. 7 Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300
Product Specification
| Host | Rat |
| Antigen | CD14 |
| Synonyms | Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; Cd14 |
| Location | Cell membrane |
| Accession | P10810 |
| Clone Number | S-R609 |
| Antibody Type | Rat mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | RAW 264.7 |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Ms |
Background
CD14 is a 375-amino-acon, pattern-recognition glycoprotein that circulates in plasma as a soluble 55 kDa fragment (sCD14) shed by GPI-anchor cleavage or exists as a 55 kDa, glycosylphosphatidylinositol-anchored membrane receptor (mCD14) on myeloid cells; in both forms it acts as the critical co-receptor for Toll-like receptor 4/MD-2, enabling innate immune detection of lipopolysaccharide and other bacterial lipoglycans, thereby triggering NF-κB–driven cytokine storms, and its serum concentration rises acutely in sepsis, making it both a biomarker and a therapeutic target for endotoxin-driven inflammation.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy