SKU: 16883099286

IGFBP-1 Protein, Human

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Description

IGFBP-1 Protein, HumanProduct Specification Species Human Synonyms Insulin like growth factor binding protein 1, IBP 1, IGF binding protein 1, IGFBP 1, Placental protein 12 (PP12) Accession P08833 Amino Acid Sequence Ala26Asn259, with C terminal His tag Expression System HEK293 Molecular Weight 35 38 kDa (Reducing) Purity >95% by Bis Tris PAGE and HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH7. 4

Product Specification


Species Human
Synonyms Insulin-like growth factor-binding protein 1, IBP-1, IGF-binding protein 1, IGFBP-1, Placental protein 12 (PP12)
Accession P08833
Amino Acid Sequence

Ala26­Asn259, with C-terminal His tag

Expression System HEK293
Molecular Weight

35-38 kDa (Reducing)

Purity >95% by Bis-Tris PAGE and HPLC
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized powder
Storage Buffer

PBS, pH7.4

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.

Reference

Trends Endocrinol Metab. 2009 May;20(4):153-62.
Cell Metab. 2015 Nov 3;22(5):811-24.

Background

IGFBP-1 is a secreted protein encoded by the IGFBP1 gene located on chromosome 7 in humans. It is a member of the insulin-like growth factor binding protein family, which consists of six high-affinity binding proteins (IGFBP-1 to -6).
Human IGFBP-1 has evolved from being viewed as a passive IGF carrier to being recognized as a dynamic, multifunctional protein with significant IGF-independent biological activities. Its primary research utility lies in its role as a sensitive biomarker for hepatic insulin sensitivity and pregnancy-related conditions. Industrially, it is harnessed for diagnostic immunoassays and explored as a novel therapeutic target. Future research is likely to further dissect its tissue-specific roles and translational potential in metabolic, bone, and neoplastic diseases.

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SKU: 16883099286

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Frank
Lexington, US
★★★★★ 5
Great fit
Size: (Pack of 1)
This is my go-to oil filter for my 2015 Toyota Sienna minivan. The filter looks good and holds up well. I have no idea how well it actually works, but it looks good.
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Reviewed in the United States on May 2, 2026
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Jorge Roman Vega
Massapequa, US
★★★★★ 5
Great filter
Size: (Pack of 1)
Perfect for my Tacoma 17
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Reviewed in the United States on January 21, 2026
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Cliente de Amazon
Phoenix, US
★★★★★ 5
Excelente
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Excelente
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Reviewed in the United States on May 31, 2026
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Juan
Los Angeles, US
★★★★★ 5
Nice
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Nice
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Reviewed in the United States on May 9, 2026
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Arun Durairaja
San Leandro, US
★★★★★ 4
Good filter, Expensive
Size: (Pack of 1)
I like the product very much. It was upto my expectations but little expensive
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Reviewed in the United States on July 24, 2023

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