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Ships within 48 hours · Estimated delivery Aug 12 - Aug 17
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For Your Every Summer RSVP, with Code: SUMMER15
Description
p16 Recombinant Rabbit mAb (S-303-1)Product Specification Host Rabbit Antigen p16 Synonyms Cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase 4 inhibitor A (CDK4I), Multiple tumor suppressor 1 (MTS 1), p16 INK4a (p16 INK4; p16INK4A), CDKN2A, CDKN2, MTS1 Immunogen Recombinant Protein Location Cytoplasm, Nucleus Accession P42771 Clone Number S 303 1 Antibody Type Recombinant mAb Application WB, ICC, ICFCM, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml
Product Specification
| Host | Rabbit |
| Antigen | p16 |
| Synonyms | Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase 4 inhibitor A (CDK4I), Multiple tumor suppressor 1 (MTS-1), p16-INK4a (p16-INK4; p16INK4A), CDKN2A, CDKN2, MTS1 |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm, Nucleus |
| Accession | P42771 |
| Clone Number | S-303-1 |
| Antibody Type | Recombinant mAb |
| Application | WB, ICC, ICFCM, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IP | 1:50 | null |
| ICC | 1:100 | null |
| ICFCM | 1:500 | null |
Background
p16 (also known as p16INK4a, cyclin-dependent kinase inhibitor 2A, CDKN2A, multiple tumor suppressor 1 and numerous other synonyms), is a protein that slows cell division by slowing the progression of the cell cycle from the G1 phase to the S phase, thereby acting as a tumor suppressor. p16 can be used as a biomarker to improve the histological diagnostic accuracy of grade 3 cervical intraepithelial neoplasia (CIN). p16 is also implicated in the prevention of melanoma, oropharyngeal squamous cell carcinoma, cervical cancer, vulvar cancer and esophageal cancer.
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