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Description
IL-13 Protein, HumanProduct Specification Species Human Synonyms Interleukin 13 Accession AAH96139 Amino Acid Sequence Gly35 Asn146 ,at the C terminus 6His tag Expression System HEK293 Molecular Weight 13. 4 KDa Purity >95% by SDS PAGE Endotoxin <0. 01EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH 7. 4. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended
Product Specification
| Species | Human |
| Synonyms | Interleukin-13 |
| Accession | AAH96139 |
| Amino Acid Sequence | Gly35-Asn146 ,at the C-terminus 6His tag |
| Expression System | HEK293 |
| Molecular Weight | 13.4 KDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.01EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, pH 7.4. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Stability & Storage | ·12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
Background
Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.
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