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Description
S-RMab® SOX10 Recombinant Rabbit mAb,PBS Only (SDT-R233)Product Specification Host Rabbit Antigen SOX10 Synonyms SOX 10, SRY related HMG box 10 protein Location Nucleus Accession P56693 Clone Number SDT R233 Antibody Type Recombinant mAb Application WB, IHC P, ICC, ICFCM Reactivity Hu, Ms, Rt Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt reconstitution, 4 C as supplied Dilution
Product Specification
| Host | Rabbit |
| Antigen | SOX10 |
| Synonyms | SOX-10, SRY-related HMG-box 10 protein |
| Location | Nucleus |
| Accession | P56693 |
| Clone Number | SDT-R233 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC | 1:500 | |
| ICC | 1:500 | |
| ICFCM | 1:500 |
Background
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and determination of cell fate. The encoded protein acts as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. SOX10 is used as an immunohistochemistry marker, diagnosis of malignant melanoma; Combined with MITF1 and it can differentiate malignant melanoma in situ from actinic keratosis; More specific for tumors originating from the neural crest than S100.
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