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Description
K9 Advantix II XL Dog Flea, Tick & Mosquito Treatment & PreventionK9 Advantix II Extra Large Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing
K9 Advantix II Extra Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Extra Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use K9 Advantix II Extra Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Extra Large Dog is a trademark of Elanco or its affiliates.
Key Features
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K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
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Kills fleas within 12 hours of application
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Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
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Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
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No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Extra Large
Pet Lifestage
- 7 weeks and older
Pet Weight
Over 55 lbs
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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4.4 ★★★★★
Based on 26 reviews
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Product Reviews
★★★★★ 5
Great Read for 11 Year Old
Format: Hardcover
My 11 year old couldn't put this one down and was a bit sad when it ended. We've already ordered another one in the series.
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Reviewed in the United States on January 6, 2026
★★★★★ 5
Be warned! You can’t put this down
Format: Hardcover
Page turner that makes it hard to put down. Loved the history and research and the storyline . My 11 year old grandson introduced me to the series and he reads them to me. Gets us closer
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Reviewed in the United States on April 6, 2026
★★★★★ 4
Good content and history
Format: Paperback
This book is an easy read for our daughter and it gives details about the war. Our family enjoys history and this author has numerous books that speak to it.
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Reviewed in the United States on January 3, 2024
★★★★★ 5
Written for kids but great for adults, too
Format: Paperback
You can’t go wrong with Alan Gratz books!
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Reviewed in the United States on April 2, 2026
★★★★★ 5
The book series that got my son into reading
Format: Hardcover
Very thankful we found this author and these books. This is the first series my son struggles to put down and the mandatory 20 minute reading time with lots of nagging has turned into gentle nudges that he has to stop reading at the next chapter because it is getting late.
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Reviewed in the United States on April 8, 2026