Mesoporous Solid-core Silica Nanoparticles (80-100 nm)

Mesoporous Solid-core Silica Nanoparticles (80-100 nm)Product Name Mesoporous Solid core Silica Nanoparticles Product Overview Mesoporous materials (pore size 2 50nm) have a pore size between microporous materials (pore size<2 nm) and macroporous materials (pore size>50 nm), and possess many excellent characteristics, such as highly ordered pore structure, single pore size distribution, and high stability, making them a hot research topic in recent years. As a common inorganic nanoparticle, silica

Product Name

Mesoporous Solid-core Silica Nanoparticles 

Product Overview

Mesoporous materials (pore size 2-50nm) have a pore size between microporous materials (pore size<2 nm) and macroporous materials (pore size>50 nm), and possess many excellent characteristics, such as highly ordered pore structure, single pore size distribution, and high stability, making them a hot research topic in recent years. As a common inorganic nanoparticle, silica nanoparticles have a series of advantages such as controllable morphology, ordered and adjustable pore structure, large specific surface area, easy modification of surface functional groups, and good biocompatibility, which make them widely used in biomedical, catalytic, environmental, optical and other fields. The main preparation method of silica nanoparticles is the sol gel method. Under the catalysis, the silicon source is formed by hydrolysis and condensation. This method was first proposed by Stober in 1968. According to the morphological characteristics of silica nanoparticles, they can be roughly divided into three types: solid silica, mesoporous silica, and hollow structured silica. Among them, the pore structure of mesoporous silica is generally formed by template method, which includes soft templates and hard templates. Soft templates are generally amphiphilic surfactants, while hard templates are generally high molecular weight polymers, with soft templates being more commonly used. The preparation process of mesoporous silicon can be divided into two stages: firstly, the template interacts with the inorganic precursor to synthesize liquid crystal structural phases with nanoscale lattice constants of organic and inorganic materials under certain conditions; Then, high-temperature heat treatment or other physical and chemical methods are used to remove the template, and the space left by the template forms mesoporous channels. The surface of silica nanoparticles has abundant silicon hydroxyl groups, which facilitate their surface chemical modification. By modifying different functional groups, silica nanoparticles can be endowed with more functions. The commonly used types of surface modifications currently include surface amination, thiolation, and organic chain functionalization. The surface modification of silica nanoparticles is mainly achieved by introducing different types of silane coupling agents, such as 3-aminopropyltriethoxysilane (APTES), which can be used for amination modification, and 3-mercaptopropyltrimethoxysilane, which can be used for thiol modification.

Technical Parameter

Form：white powder

Size:0-100 nm

Specific surface area:~800 m2/g

Pore volume:.55 cm2/g

Average pore size:-5 nm

Application Fields

1. High specific surface area: It can provide a large number of active sites, enhance interactions with other substances, load more catalysts in catalytic reactions, and improve reaction efficiency.

2. Ordered mesoporous structure: The pore size is uniform and adjustable, which is conducive to the transport and diffusion of substances. In drug delivery, the release rate of drug molecules can be controlled.

3. Good thermal and chemical stability: able to maintain structural and performance stability in high temperatures and various chemical environments.

4. Strong surface modifiability: It is easy to functionalize its surface through chemical methods to meet different application requirements.

5. Good biocompatibility: When applied in the biomedical field, it usually has low toxicity to organisms and high safety.

Product Features

1. Drug delivery: Loading anti-cancer drugs into the pores of mesoporous silica to achieve slow drug release. By surface modification, drugs can target specific tumor cells, improving therapeutic efficacy while reducing damage to normal cells.

2. Biological imaging: Load fluorescent molecules (FITC, Cy5.5) or magnetic nanoparticles for imaging cells and in vivo, achieving real-time monitoring of intracellular biological processes.

3. Gene therapy: As a gene carrier, it protects the stability and transmission efficiency of genes in the body.

4. Diagnostic reagents: used to detect biomarkers, such as molecules loaded with specific recognition of disease-related markers, to achieve early diagnosis of diseases.

5. Organizational engineering: As a scaffold material, it promotes cell growth and tissue regeneration.

Related Information

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