SKU: 80450254112

Protopic

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Description

ProtopicProtopic Description Protopic is a cream used on the skin to treat inflammation, such as perioral dermatitis. It blocks calcineurin, a protein that triggers your body's inflammatory cells, helping to reduce inflammation. Apply it twice daily until the affected area improves, then switch to twice a week to maintain your condition. Essential Information What is Protopic? Protopic ointment includes tacrolimus, which helps to lessen inflammation and

Protopic Description
Protopic is a cream used on the skin to treat inflammation, such as perioral dermatitis.
It blocks calcineurin, a protein that triggers your body's inflammatory cells, helping to reduce inflammation.
Apply it twice daily until the affected area improves, then switch to twice a week to maintain your condition.

What is Protopic?

Protopic ointment includes tacrolimus, which helps to lessen inflammation and itching. It's used to treat different types of dermatitis (skin irritation) when the condition is believed to be caused by an immune response.

Perioral dermatitis appears as a red rash around the mouth, often accompanied by itchiness and spots. The exact cause isn't completely known, but some believe that inflammation of the hair follicles might lead to spots forming around the mouth. Although topical steroids are commonly used to treat this condition, overuse can cause dermatitis when you stop using them. Other possible causes include hormonal changes, taking oral contraceptives, and fungal infections.

How does Protopic work?

Protopic contains tacrolimus, which is an immunomodulating agent that influences your immune system. When you apply it to your skin, it blocks calcineurin, which helps reduce inflammatory substances like mast cells, cytokines IL-2, and TNF-alpha. Consequently,

How is Protopic different from other treatments for perioral dermatitis?

Protopic is a type of immunosuppressant. It works by dampening the immune response, which helps to lessen inflammation and itching. Elidel is a similar medication to Protopic. It contains pimecrolimus, which also helps to reduce inflammation and is used to treat dermatitis.

If the affected area is severely infected, your doctor might prescribe antibiotics such as Lymecycline for a few weeks. This helps stop the bacteria causing the infection, which can ease itching and also reduce inflammation and spots.

How well does Protopic work for perioral dermatitis?

Tacrolimus has been shown to effectively treat dermatitis. A study from 2000 revealed that patients using 0.1% tacrolimus twice a day experienced noticeable improvements within a week (54%), with even better results after 6 months (81%) and a year (86%).

Moreover, when comparing tacrolimus to topical corticosteroids for treating atopic dermatitis, 71.6% of patients using tacrolimus showed more improvement within 3 months, compared to 50.8% of those using a steroid.

Important Information

Protopic isn't right for everyone, and there are a few things you should know when using it.

Here's all the official information on it. If anything isn't clear, just let our clinician know, and they can discuss it with you.

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SKU: 80450254112

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★★★★★ 5
I like this brand of clothing, let’s keep them around.
Size: X-Large, Color: Brown
Great quality great fit.
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Reviewed in the United States on May 5, 2026
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Robert Smith
Houston, US
★★★★★ 5
Well made but on the small side. I recommend ordering one size bigger than your usual size
Size: Large, Color: Pure Black (Retro Rose)
The fit on this shirt ran slightly smaller for me being a slim fit, so I order the next size up. Getting the next size up gave me a perfect fit. The material is soft and comfortable. I will likely consider similar shirts in the future. I recommend the product.
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Reviewed in the United States on April 30, 2026
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Lauren
Massapequa, US
★★★★★ 5
Cowboy shirt
Size: Large, Color: White
Good quality. Fit and finish seem nice for the price. Look like a cowboy! Yeee haaaaaw. Wrinkles easy in dryer, don’t let it sit for long.
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Reviewed in the United States on March 4, 2026
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Otis H.
Fort Morgan, US
★★★★★ 4
Very nice shirt -Good Quality
Size: XX-Large, Color: Red (Retro Rose)
My husband is 6'1, weighs 178 pounds and normally wears a medium or large. Just for reference his pant size is a 32-34 depending on the brand. We ordered a large due to the fact the shirt appeared to be fitted more at the waist and from looking at the description I knew it would not have much stretch due to the satin type material. I was right. The large fit perfect and hung well. My husband use to be very large in shoulders and arms, but with age he has lost muscle mass, and recently lost a lot in his belly, so usually mediums fit perfect now. But when he put his large on, a medium would not have fit good to be comfortable & give proper fit in stomach area, so glad we went with the large. The shirt was purchased to go on a Virgin Cruise for Scarlett night, and he plans to wear black pants with it as in the picture the company posted, and this shirt will be perfect for that. It is a nice shirt, good quality, and if someone wanted it for an event/cruise or just for a night to dress up, especially for a Caribbean/Spanish or Latin dance theme, this shirt is a perfect look to me. Buy it, you will not be disappointed. He has not worn it yet, not washed it, but I would not put in it with other colors, may fade a little like reds do, and definitely, only dry on low/delicate. May need a pressing/steaming, but overall, it was not horribly wrinkled when we received it. A toss in the dryer may just do the trick. Was delivered on time as it said it would. Hope this info helps you.
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Reviewed in the United States on January 14, 2024
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Avery Hughes
Pawtucket, US
★★★★★ 5
Yeehaw!
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