SKU: 75445417064

Malignant : How Bad Policy and Bad Evidence Harm People with Cancer

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Malignant : How Bad Policy and Bad Evidence Harm People with CancerHow hype, money, and bias can mislead the public into thinking that many worthless or unproven treatments are effective. Each week, people read about new and exciting cancer drugs. Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In

How hype, money, and bias can mislead the public into thinking that many worthless or unproven treatments are effective. Each week, people read about new and exciting cancer drugs. Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel-but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which* promote novel cancer therapies long before credible data are available to support such treatment; and* exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars. Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration. This is a book about how the actions of human beings-our policies, our standards of evidence, and our drug regulation-incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says, * more cancer clinical trials should measure outcomes that actually matter to people with cancer;* patients on those trials should look more like actual global citizens;* we need drug regulators to raise, not perpetually lower, the bar for approval; and* we need unbiased patient advocates and experts. This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer-and how we can avoid repeating the policy and practice mistakes of the past.

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SKU: 75445417064

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4.1 ★★★★★
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Erika
Lowell, US
★★★★★ 5
Amazing!!
The dogs love them!!! They have not been able to destroy them at all!!
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Reviewed in the United States on May 30, 2026
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Verified Purchase
BrandiLynn0311
Natrona Heights, US
★★★★★ 5
Mixed Results: SIHRMIU Dog Chew Toys Offered Stimulation, Limited Interest from Aggressive Chewers
I recently purchased the SIHRMIU 2 Pack Dog Chew Toys for Aggressive Chewers with hopes of providing my energetic dogs with both entertainment and stimulation. While these toys boasted durability and were designed to alleviate boredom, my experience with them yielded mixed results. Upon receiving the chew toys, I appreciated their sturdy construction and the promise of durability, which was essential given my dogs' penchant for aggressive chewing. The variety of textures and shapes seemed promising, offering potential for engaging play sessions that could keep my pets occupied and mentally stimulated. Initially, my dogs showed some interest in the toys, eagerly sniffing and exploring them. They seemed intrigued by the different textures and shapes, and I was hopeful that these toys would provide the entertainment they needed. However, as my dogs began to interact more with the toys, it became evident that their interest was short-lived. While they engaged with the toys for brief periods, they quickly lost interest and returned to their usual chewing favorites. Despite their designation for aggressive chewers, the toys did not seem to withstand the intense chewing of my pets as well as expected. Within a short time, I noticed signs of wear and tear, with pieces starting to break off. While the SIHRMIU dog chew toys offered some stimulation and diversion for my dogs, they ultimately failed to hold their interest or stand up to their aggressive chewing habits. While they may be suitable for dogs with less voracious chewing tendencies, they were not a perfect fit for my pets. In conclusion, while these chew toys have potential and may work well for some dogs, they fell short of expectations for my aggressive chewers. I appreciate the effort put into their design and durability, but unfortunately, they did not meet the needs of my furry companions.
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Reviewed in the United States on March 29, 2024
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Michele Johnson
Grantham, US
★★★★★ 5
Indestructible!
These dog chew toys have been a great purchase! My dog loves them and was interested in them right away. The shapes are fun and easy for my dog to hold while chewing, which keeps them entertained for a long time. The material feels durable and has held up really well even with regular chewing. I also like that it helps keep my dog busy and gives them something safe to chew on instead of furniture or shoes. Getting two toys in the pack is a nice bonus, and they seem well made for the price. Overall, I’m very happy with this purchase and would definitely recommend these chew toys to other dog own
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Reviewed in the United States on March 11, 2026
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Deanna Yanda
Los Angeles, US
★★★★★ 5
Indestructible for the heavy chewers in your life!
My dogs can chew anything, and these are still in great shape! Very chew resistant to even my large dogs, and they love them! Easy to wash off if they end up in the food bowl or outside!
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Reviewed in the United States on May 27, 2026
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Annie
West Palm Beach, US
★★★★★ 5
Perfect for aggressive chewers
Super durable and my dog loves it! Keeps her busy and she’s a very aggressive chewer
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Reviewed in the United States on April 4, 2026

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